| | | | | | |
  当前位置:首页 > 团队科研成果 

Neural circuit and its functional roles in cerebel
作者:数学建模与神经计算 发布日期:2019-2-23
 点击:1133
关键词:-

Neural circuit and its functional roles in cerebellar cortex

Lei WANG, Shen-Quan LIU


Abstract:  Objective   To investigate the spike activities of cerebellar cortical cells in a computational network model con -structed based on the anatomical structure of cerebellar cortex.  Methods and Results   The multicompartment model of neuron and NEURON software were used to study the external influences on cerebellar cortical cells. Various potential spike patterns in these cells were obtained. By analyzing the impacts of different incoming stimuli on the potential spike of Purkinje cell, temporal focusing caused by the granule cell-golgi cell feedback inhibitory loop to Purkinje cell and spa -tial focusing caused by the parallel fiber-basket/stellate cell local inhibitory loop to Purkinje cell were discussed. Finally, the motor learning process of rabbit eye blink conditioned reflex was demonstrated in this model. The simulation results showed that when the afferent from climbing fiber existed, rabbit adaptation to eye blinking gradually became stable under the Spike Timing-Dependent Plasticity (STDP) learning rule.  Conclusion    The constructed cerebellar cortex network is a reliable and feasible model. The model simulation results confirmed the output signal stability of cerebellar cortex after STDP learning and the network can execute the function of spatial and temporal focusing.

/Uploads/file/20190223/20190223205162936293.pdf





收 藏 推 荐 打 印 关 闭
上一篇:Codimension-two bifurcation analysis in two-dimens 下一篇:神经元的形态分类和识别
   关于我们
s
s
   推荐产品
   图片文章
   最新资讯
二次整合和放电神经元网络中的跨尺度兴奋性
具有二阶突触的精确和启发式神经质量模型...
一个具有突触延迟的大的峰值神经元系统的...
具有短期突触可塑性的峰值神经元网络的平...
排斥抑制在兴奋网络同步中的协同效应
具有双峰异质性的二次整合-触发神经元网...
 
友情链接: 神经计算   国家自然科学基   华南理工大学   全国大学生数学   美国数学建模竞   MATLAB  
咨询热线:刘教授 13650823684 邮箱:liushenat@sohu.com 备案编号:豫ICP备18005949号
地址:广州市番禺区广州大学城 邮编:510006  技术支持:郑州建网站 本站域名:mashqliu.com
Copyright © 2018-2024 数学建模与神经计算 Inc, All Rights Reserved.
在线客服
刘教授 13650823684
客服代表
点击这里给我发消息